Computational biology for ageing

Computational biology for ageing

High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in order to pinpoint the causes and effects of ageing. Here, we provide a description of the existing databases and computational tools on ageing that are available for researchers. We also describe t...

The Biology of Human Ageing

setts. This book is an account of his medical education at Yale, based on a diary of his day-to-day activities and feelings during medical school. The author describes the events at Yale which were significant in his medical training, as well as the practical and ethical issues which one encounters in and after medical school. These accounts reveal to us his personal struggle with the obstacles...

The new biology of ageing

Human life expectancy in developed countries has increased steadily for over 150 years, through improvements in public health and lifestyle. More people are hence living long enough to suffer age-related loss of function and disease, and there is a need to improve the health of older people. Ageing is a complex process of damage accumulation, and has been viewed as experimentally and medically ...

A Glossary for Computational Biology

This glossary represents my current best understanding of these notions, and consolidates definitions from my own publications and working notes. Since others have found it useful in several different contexts, I now post it. Many of these definitions are not novel, though I have attempted to clarify the formal mathematical and computational definitions for nonmathematical readers. Similarly, I...

Algebraic Statistics for Computational Biology